Some people swear
by acupuncture. They'll tell you how a few painless
sessions as a human pincushion cured vicious migraines or relentless back
pain. Others remain skeptical, dismissing the ancient practice as
mumbo jumbo. Now, scientists investigating its actions in heart
disease have found not only that acupuncture works, but why and how. One day, they
tell WebMD, that blood pressure medication
might be replaced by a few pins and needles.
John C. Longhurst, MD, PhD, first
became interested in acupuncture on a research trip to China. "I met an
investigator who'd been doing work in acupuncture for years. I saw that he was
a very good scientist," he says. "I, like most scientists, thought
acupuncture was a lot of hocus pocus. But when I saw his work, I knew there was
something to it."
Once home, Longhurst, a professor of
medicine at the University of California, Irvine, College of Medicine, began
the first of four investigations into the underlying mechanisms of acupuncture.
In it, his team tested cats with heart disease. "We showed that acupuncture
helped the animals by reducing ischemia -- the lack of oxygen to the heart"
caused when blood vessels are blocked, he says. That was hard
evidence that the therapy worked. Next, they tried to determine how it was
happening.
In acupuncture, invisible pathways
connecting one body part to another are called meridians. "They are
located over major [nerve] pathways that are accessed when you put a needle
in," says Longhurst. Stimulating the pathway "sends impulses to the brain,
activating different areas." Some affect pain, "which explains why
acupuncture can control pain," he says, "and others regulate the
cardiovascular system."
One such area, just above the spinal
cord in the brain stem, regulates release of adrenaline -- a
chemical that makes hearts pound and blood pressure soar. But when they induced
an "adrenaline rush" in animals, acupuncture "prevented this
from occurring. It blocked the effect," says Longhurst. Hearts beat normally
and blood pressure remained low.
In the third study, the team found
they could reverse acupuncture's heart-healthy effects by injecting cats with a
synthetic version of naturally occurring opioids -- brain chemicals that produce a "runner's high,"
kicking in when we're in severe pain. "So, we're narrowing it down,
getting more specific and detailed in terms of what's going on," says
Longhurst.
A fourth study is underway in human
subjects, he tells WebMD, but it's still too early to draw any conclusions.
The ultimate goal of this work is to
help the huge number of patients with ischemia, high blood pressure, and irregular heart beat, or
heart arrhythmias, he tells WebMD. "The current meds have a lot of side
effects. If we can reduce [their medication needed] with acupuncture, that
would be great."
Experts agree it's not a far-fetched
idea. "There has to be something more to acupuncture than the placebo effect or hypnosis," says Joseph
Alpert, MD, Flinn Professor of Medicine and chairman of the department of
medicine at the University of Arizona in Tucson. "My colleagues have seen
people have open heart surgery with only acupuncture, no anesthesia. This is
not a bunch of malarkey," he tells WebMD, "it's real."
Pascal J. Goldschmidt, MD, FACC,
chief of cardiology at Duke University, agrees. "It's not an accident that
people have been doing acupuncture for so long," he tells WebMD. The
findings are "pretty clear that it's not a placebo effect. Acupuncture
seems to be having a relatively specific effect on the control of blood
pressure."
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